• Report
  • February 6, 2019

Battling Sepsis is Bigger Than Your Team

Join a collaborative for children’s hospitals to improve sepsis outcomes and save lives.

Join the sepsis initiative exclusively for children’s hospitals that will save thousands of lives and hundreds of millions of dollars in costs every year. Our opportunity for impact is enormous because the sepsis problem is enormous.

Sepsis is the leading cause of death in hospitalized children, killing almost 5,000 children annually in the U.S., more than cancer. Sepsis is expensive; costs to treat severe sepsis range from $65,000 to $85,000. It accounts for 16 percent of all pediatric health care spending–around $5 billion. As many as 80,000 children are hospitalized annually for sepsis and 65 percent of those children are treated in children’s hospitals.

Children's Hospitals Respond

Whether your organization is getting started in the fight against sepsis, or has an in- house sepsis program in place, the Improving Pediatric Sepsis Outcomes (IPSO) collaborative will accelerate your progress to improved outcomes. Children’s hospitals large and small are benefiting and contributing.

Participating hospitals have access to bundles addressing diagnosis and treatment, the experience of children’s hospitals working at the leading edge to improve sepsis outcomes, and the largest pool of clinical pediatric sepsis data available.

Results You Can Expect

As participants in the IPSO collaborative, clinicians in your hospital will have the knowledge to:

  • Prevent avoidable deaths from sepsis
  • Prevent escalation to severe sepsis in vulnerable patients
    • Identify all patients with sepsis risk
    • Recognize sepsis and sepsis risk earlier
    • Shorten ICU and hospital stays
    • Improve sepsis resuscitation
  • Prevent avoidable long-term disabilities
  • Create effective sepsis response systems across the hospital


Submit a letter of commitment to enroll in IPSO. Executive engagement and sponsorship are critical to achieving hospital- wide results. To achieve IPSO’s ambitious aims, plan to participate for three years and work across the hospital, rather than within one or two units.

Participation Criteria

The collaborative is open to any hospital that is a member of Children’s Hospital Association (CHA).