Improving Pediatric Sepsis Outcomes (IPSO) is a national collaborative of children’s hospitals that aims to improve pediatric sepsis outcomes through early identification and timely treatment. IPSO members contribute to the largest pool of clinical pediatric sepsis data in the U.S., and their work continues to show progress.
Recent analysis of the collaborative’s data suggests complying with IPSO-recommended clinical bundles helps to significantly improve patient outcomes. Clinical teams use the bundles, a set of collaborative-defined five key processes.
The collaborative recommends using at least one of the three recognition processes—sepsis screening, a sepsis huddle or order set utilization—and focusing on timely administration of first fluid bolus and first IV antibiotic.
Participant data demonstrates consistent use of the IPSO-defined bundles results in better outcomes. Bundle compliance reduced sepsis-attributable mortality and hospital days.
Sepsis-attributable mortality is 48% lower in compliant episodes than in non-compliant episodes. Median hospital days per sepsis episode are 33% lower in compliant episodes than in non-compliant episodes. Hospitals can use the formula to improve care.
