Defining, Developing and Understanding Pediatric Sepsis Outcomes

Defining, Developing and Understanding Pediatric Sepsis Outcomes

Peer reviewed articles from the Improving Pediatric Sepsis Outcomes collaborative outline the effort to challenge sepsis.

Improving Pediatric Sepsis Outcomes (IPSO) is a collaborative dedicated to reducing sepsis-attributable mortality and improving survivor outcomes. As IPSO participants lead these quality improvement efforts, results include: 

Evaluating Pediatric Sepsis Definitions: A description of IPSO definitions' effectiveness for large-scale data abstraction, identifying patients treated for sepsis, as well as practical utility for use in quality improvement. The definitions demonstrated feasibility for large-scale data abstraction. The definitions also indicated strengths in content validity, convergent construct validity, and criterion validity; weakness in reliability.

Developing a Quality Improvement Collaborative: A description of the development of the learning collaborative and details the aims and key drivers based on treatment guidelines, evidence and baseline data.

Metric Development: A comprehensive data dictionary was developed for the largest pediatric sepsis QI collaborative, optimizing automation and ensuring sustainable reporting. These approaches can be used in other large-scale sepsis QI projects in which researchers leverage EHR data abstraction.

As the IPSO collaborative wraps up, check back for additional manuscripts, findings and information.


About Sepsis

Sepsis is a leading cause of death in hospitalized children, and children’s hospitals are dedicated to improving outcomes through collaboration, early identification and timely treatment.

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